Lehrstuhl für Mechanische Verfahrenstechnik (MVT)

Particle formulation

For various products, e.g. in the pharmaceutical, chemical and food industries, the formulation of solid particles with different substances is an important production step. At the Institute of Particle Process Engineering numerical simulation tools are used to develop new apparatus, to gain further information about particle motion and to optimize special particle processes, e.g. spheronization of cylindrical particles or coating of particles.
The current project in this area is called "Analysis of fluidization and shear conditions in rotor fluid beds under dry and wet conditions". The influence of fluid and particle shape on particle dynamics in a dense, sheared gas-solid flow is investigated. Granulation and coating are modeled with a CFD-DEM approach. Using the example of a rotor fluidized bed, detailed experimental investigations of the particle dynamics are carried out using a novel MPT measuring technique under dry and wet conditions (spraying liquids).


Research Areas

Recent Publications

  • Dominik Weis, Philipp Grohn, Maria Evers, Markus Thommes, Edwin García, Sergiy Antonyuk (2020): “Implementation of formation mechanisms in DEM simulation of the spheronization process of pharmaceutical pellets”, Powder Technology. doi.org/10.1016/j.powtec.2020.09.013
  • Philipp Grohn, Marius Lawall, Tobias Oesau, Stefan Heinrich, Sergiy Antonyuk (2020): “CFD-DEM Simulation of a Coating Process in a Fluidized Bed Rotor Granulator”, Processes 8 (9), S. 1090. DOI: 10.3390/pr8091090
  • Philipp Grohn, Dominik Weis, Markus Thommes, Stefan Heinrich, Sergiy Antonyuk (2020): “Contact behavior of MCC pellets depending on their water content”, Chemical Engineering & Technology 2020, doi.org/10.1002/ceat.201900517
  • Weis, D.; Krull, F.; Mathy, J.; Evers, M.; Thommes, M.; Antonyuk, S.: A contact model for the deformation behaviour of pharmaceutical pellets under cyclic loading, Advanced Powder Technology (2019), In Press, doi.org/10.1016/j.apt.2019.07.026
  • Weis, D.; Niesing, M.; Thommes, M.; Antonyuk, S.: DEM simulations of the mixing behavior in a spheronization process, Chemical Engineering Science 192 (2018), 803-815, doi.org/10.1016/j.ces.2018.07.057
  • Breuninger, P.; Weis, D.; Behrendt, I.; Grohn, P.; Krull, F.; Antonyuk, S.: CFD-DEM simulation of fine particles in a spouted bed apparatus with a Wurster tube, Particuology (2018), doi.org/10.1016/j.partic.2018.03.015
  • Weis, D.; Niesing, M.; Thommes, M.; Antonyuk, S.: Partikelkinematik in der Sphäronisation pharmazeutischer Pellets, Chemie Ingenieur Technik (2017), doi.org/10.1002/cite.201600154
  • Vafaeezadeh, M., Wilhelm, C., Breuninger, P., Ernst, S., Antonyuk, S. and W. R. Thiel: A Janus-type heterogeneous phase transfer catalyst for adipic acid synthesis, ChemCatChem (2020) dx.doi.org/10.1002/cctc.202000140
  • M. Vafaeezadeh, P. Breuninger, P. Lösch, C. Wilhelm, S. Ernst, S. Antonyuk, W. Thiel: Janus Interphase Organic‐Inorganic Hybrid Materials: Novel Water‐Friendly Heterogeneous Catalysts, ChemCatChem (2019), doi.org/10.1002/cctc.201900147


Laboratory Equipment

Spouted bed apparatus

In house developed apparatus for coating of very finde (Geldart C) particles


Optical analysis of the particle size, form and roughness


Meaurements of the particle defor-mation behaviour depending on the temperature, particle roughness

Texture Analyser

Meaurements of the particle deformation behaviour depending on the temperature and air humidity and meaurements of particle friction coefficients

High speed cameras

Measurement of dynamic impact of par-ticle / droplet

Simulation Tools

  • ANSYS CFX, ANSYS Fluent   
  • OpenFOAM   
  • LIGGGHTS / CFDEMcoupling   
  • EDEM solutions    
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